Lovely firefly!

If unaligned multimodal medical images can be simultaneously aligned and fused using a single-stage approach within a unified processing framework, it will not only achieve mutual promotion of dual tasks but also help reduce the complexity of the model. However, the design of this model faces the challenge of incompatible requirements for feature fusion and alignment. To address this challenge, this paper proposes an unaligned medical image fusion method called Bidirectional Stepwise Feature Alignment and Fusion (BSFA-F) strategy. To reduce the negative impact of modality differences on cross-modal feature matching, we incorporate the Modal Discrepancy-Free Feature Representation (MDF-FR) method into BSFA-F. MDF-FR utilizes a Modality Feature Representation Head (MFRH) to integrate the global information of the input image. By injecting the information contained in MFRH of the current image into other modality images, it effectively reduces the impact of modality differences on feature alignment while preserving the complementary information carried by different images. In terms of feature alignment, BSFA-F employs a bidirectional stepwise alignment deformation field prediction strategy based on the path independence of vector displacement between two points. This strategy solves the problem of large spans and inaccurate deformation field prediction in single-step alignment. Finally, Multi-Modal Feature Fusion block achieves the fusion of aligned features. The experimental results across multiple datasets demonstrate the effectiveness of our method.

多模态医学图像分割：多模态医学图像分割指融合多模态图像的信息以提高分割性能。常见的医学图像主 要有计算机断层扫描（Computed Tomography， CT）、磁共振成像（Magnetic Resonance Imaging， MRI）和正电子发射断层扫描（Positron Emission computed Tomography， PET）等。

U-Net is a widely used model for medical image segmentation, renowned for its strong feature extraction capabilities and U-shaped design, which incorporates skip connections to preserve critical information. However, its decoders exhibit information-specific preferences for the supplementary content provided by skip connections, instead of adhering to a strict one-to-one correspondence, which limits its flexibility across diverse tasks. To address this limitation, we propose the Task-Adaptive Mixture of Skip Connections (TA-MoSC) module, inspired by the Mixture of Experts (MoE) framework. TA-MoSC innovatively reinterprets skip connections as a task allocation problem, employing a routing mechanism to adaptively select expert combinations at different decoding stages. By introducing MoE, our approach enhances the sparsity of the model, and lightweight convolutional experts are shared across all skip connection stages, with a Balanced Expert Utilization (BEU) strategy ensuring that all experts are effectively trained, maintaining training balance and preserving computational efficiency. Our approach introduces minimal additional parameters to the original U-Net but significantly enhances its performance and stability. Experiments on GlaS, MoNuSeg, Synapse, and ISIC16 datasets demonstrate state-of-the-art accuracy and better generalization across diverse tasks. Moreover, while this work focuses on medical image segmentation, the proposed method can be seamlessly extended to other segmentation tasks, offering a flexible and efficient solution for diverse applications.

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Centre des Mat´eriaux、Centre de Mise en Forme des Mat´eriaux、Centre de Morphologie Math´ematique

Transformers have recently gained considerable popularity for capturing long-range dependencies in the medical image segmentation. However, most transformer-based segmentation methods primarily focus on modeling global dependencies and fail to fully explore the complementary nature of different dimensional dependencies within features. These methods simply treat the aggregation of multi-dimensional dependencies as auxiliary modules for incorporating context into the Transformer architecture, thereby limiting the model’s capability to learn rich feature representations. To address this issue, we introduce the Dual Attention Encoder with Joint Preservation (DANIE) for medical image segmentation, which synergistically aggregates spatial-channel dependencies across both local and global areas through attention learning. Additionally, we design a lightweight aggregation mechanism, termed Joint Preservation, which learns a composite feature representation, allowing different dependencies to complement each other. Without bells and whistles, our DANIE significantly improves the performance of previous state-of-the-art methods on five popular medical image segmentation benchmarks, including Synapse, ACDC, ISIC 2017, ISIC 2018 and GlaS.

在DRIVE数据集上的改进效果预估：

Medical image segmentation methods based on deep learning network are mainly divided into CNN and Transformer. However, CNN struggles to capture long-distance dependencies, while Transformer suffers from high computational complexity and poor local feature learning. To efficiently extract and fuse local features and long-range dependencies, this paper proposes Rolling-Unet, which is a CNN model combined with MLP. Specifically, we propose the core R-MLP module, which is responsible for learning the long-distance dependency in a single direction of the whole image. By controlling and combining R-MLP modules in different directions, OR-MLP and DOR-MLP modules are formed to capture long-distance dependencies in multiple directions. Further, Lo2 block is proposed to encode both local context information and long-distance dependencies without excessive computational burden. Lo2 block has the same parameter size and computational complexity as a 3×3 convolution. The experimental results on four public datasets show that Rolling-Unet achieves superior performance compared to the state-of- the-art methods.